Synthesis, Characterization and In Vitro Study of Biocompatible Cinnamaldehyde Functionalized Magnetite Nanoparticles (CPGF Nps) For Hyperthermia and Drug Delivery Applications in Breast Cancer

@inproceedings{Wani2014SynthesisCA,
  title={Synthesis, Characterization and In Vitro Study of Biocompatible Cinnamaldehyde Functionalized Magnetite Nanoparticles (CPGF Nps) For Hyperthermia and Drug Delivery Applications in Breast Cancer},
  author={Kirtee D. Wani and Brijesh S. Kadu and Prakash P. Mansara and Preeti Gupta and Avinash V. Deore and Rajeev C. Chikate and Pankaj Poddar and Sanjay D. Dhole and Ruchika Kaul-Ghanekar and Alexander V Ljubimov},
  booktitle={PloS one},
  year={2014}
}
Cinnamaldehyde, the bioactive component of the spice cinnamon, and its derivatives have been shown to possess anti-cancer activity against various cancer cell lines. However, its hydrophobic nature invites attention for efficient drug delivery systems that would enhance the bioavailability of cinnamaldehyde without affecting its bioactivity. Here, we report the synthesis of stable aqueous suspension of cinnamaldehyde tagged Fe3O4 nanoparticles capped with glycine and pluronic polymer (CPGF NPs… CONTINUE READING
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