Syntheses of some α-cyclic tripeptides as potential inhibitors for HMG-CoA Reductase

Abstract

α-Cyclic tripeptides (CtPs) are the most rigid members of the cyclic peptide family. However, due to their synthetic difficulty, biological activity has remained undisclosed. The incorporation of side-chain-protected natural amino acids into functional CtPs was performed to explore the potential biological functions. Several novel CtPs that consist of… (More)
DOI: 10.1007/s00726-015-1977-2

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