Syntheses of novel heterocycles as anticancer agents.

  title={Syntheses of novel heterocycles as anticancer agents.},
  author={Prem M S Chauhan and Cristina J A Martins and David C. Horwell},
  journal={Bioorganic & medicinal chemistry},
  volume={13 10},
Several pteridine analogues 4-13, 23-26 have been synthesized and tested in vitro against three cancer cell lines, MCF7 (breast), NCI-H460 (lung) and SF-268 (CNS). All tested pteridines can serve as novel templates for the anticancer chemotherapy and can serve as new leads in cancer chemotherapy.