Syntheses and conformational studies of poly‐β,N‐alkyl L‐asparagines

@article{Hayakawa1972SynthesesAC,
  title={Syntheses and conformational studies of poly‐$\beta$,N‐alkyl L‐asparagines},
  author={Tadao Hayakawa and H Yamamoto and Naomi Aoto},
  journal={Biopolymers},
  year={1972},
  volume={11}
}
Several β,N‐alkyl L‐asparagines were prepared from the phthalyl and benzyloxycarbonyl derivatives. High‐molecular‐weight poly‐β,N‐benzyl L‐asparagine and poly‐β,N‐(1)‐phenethyl L‐asparagine were prepared from the corresponding N‐carboxyanhy‐drides. From the results obtained by a study of the infrared absorption spectra and the optical rotatory dispersion, poly‐β‐N‐benzyl L‐asparagine was found to be a random coil structure in dichloroacetic acid and the optical rotatory dispersion curves… Expand
2 Citations
Synthesis and conformational study of poly(Nϵ‐benzyl‐L‐lysine) and its benzyloxycarbonyl derivative
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The solvent‐and pH‐induced conformational changes are examined in order to investigate the influence of benzyl group and the breakdown of the helical conformation is found to occur at 8% dichloroacetic acid in chloroform‐dichloroACetic acid mixture. Expand
Syntheses and Conformational Studies of Polyacidic Amino Acids Containing Optical Active Side Chains
The syntheses and physicochemical properties of poly ( β-alkyl aspartate) and poly( γ-alkyl glutamate) have been widely investigated (1–11). Optical rotatory dispersion (ORD) and circular dichroismExpand

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TLDR
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