Corpus ID: 101411952

Syntheses and Crystal Structures of Two New α-Aminophosphonate Derivatives Containing Thieno(2,3-d)pyrimidine ①

@inproceedings{Zhu2015SynthesesAC,
  title={Syntheses and Crystal Structures of Two New α-Aminophosphonate Derivatives Containing Thieno(2,3-d)pyrimidine ①},
  author={Zhu and Xi-feng and Guo and Yan-chun and Yu. and Zhi-Ran and Liao and Xin-cheng and Zhao and Yu-fen},
  year={2015}
}
  • Zhu, Xi-feng, +7 authors Yu-fen
  • Published 2015
  • Chemistry
    • Two new α-aminophosphonate derivatives containing thieno(2,3-d)pyrimidine, diethyl(((6-ethyl-2-methyl-4-oxothieno(2,3-d)pyrimidin-3(4H)-yl)amino)(4-methoxyphenyl)methyl) phosphonate (1) and diethyl((4-bromophenyl)((6-ethyl-2-methyl-4-oxothieno(2,3-d)pyrimidin-3 (4H)-yl)amino)methyl)phosphonate (2), have been synthesized by a facial phosphorylated reaction, and their structures were characterized by NMR, IR, HRMS and X-ray single-crystal diffraction. Compound 1 (C21H28N3O5PS, Mr = 465.49… CONTINUE READING

    References

    SHOWING 1-10 OF 17 REFERENCES
    Synthesis and Crystal Structure of 5,7-Dimethoxy-2-phenylquinolin-4-yl Phenyloxy (N-L-Alanine ethyl ester) Phosphoramidate
    • 2
    Synthesis and antiviral bioactivities of 2-cyano-3-substituted-amino(phenyl) methylphosphonylacrylates (acrylamides) containing alkoxyethyl moieties.
    • 18
    Synthesis, analgesic, anti-inflammatory, ulcerogenic index and antibacterial activities of novel 2-methylthio-3-substituted-5,6,7,8-tetrahydrobenzo (b) thieno[2,3-d]pyrimidin-4(3H)-ones.
    • 95
    Antimicrobial investigations on synthetic p-tolylazo derivatives of thienopyrimidinone based on an ortho funtionalized thiophene nucleus
    • 13
    Synthesis, X-ray crystallographic analysis, and antitumor activity of N-(benzothiazole-2-yl)-1-(fluorophenyl)-O,O-dialkyl-α-aminophosphonates
    • 101
    Synthesis and antibacterial activity of some novel triazolothienopyrimidines.
    • 15
    • PDF
    The identification of 2-(1H-indazol-4-yl)-6-(4-methanesulfonyl-piperazin-1-ylmethyl)-4-morpholin-4-yl-thieno[3,2-d]pyrimidine (GDC-0941) as a potent, selective, orally bioavailable inhibitor of class I PI3 kinase for the treatment of cancer .
    • 623
    Discovery of novel thieno[2,3-d]pyrimidin-4-yl hydrazone-based inhibitors of Cyclin D1-CDK4: synthesis, biological evaluation, and structure-activity relationships.
    • 75
    Synthesis and DHFR inhibitory activity of a series of 6-substituted-2,4-diaminothieno[2,3-d]pyrimidines.
    • 36
    Synthesis and screening of some novel fused thiophene and thienopyrimidine derivatives for anti-avian influenza virus (H5N1) activity.
    • 80