Syntabulin, a motor protein linker, controls dorsal determination.

  title={Syntabulin, a motor protein linker, controls dorsal determination.},
  author={Hideaki Nojima and Sophie Rothh{\"a}mel and Takashi Shimizu and Cheol-Hee Kim and Shigenobu Yonemura and Florence L Marlow and Masahiko Hibi},
  volume={137 6},
In amphibian and teleost embryos, the dorsal determinants (DDs) are believed to be initially localized to the vegetal pole and then transported to the prospective dorsal side of the embryo along a microtubule array. The DDs are known to activate the canonical Wnt pathway and thereby promote the expression of genes that induce the dorsal organizer. Here, by identifying the locus of the maternal-effect ventralized mutant tokkaebi, we show that Syntabulin, a linker of the kinesin I motor protein… CONTINUE READING

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