Synovial stromal cells from rheumatoid arthritis patients attract monocytes by producing MCP-1 and IL-8

@article{Hayashida2001SynovialSC,
  title={Synovial stromal cells from rheumatoid arthritis patients attract monocytes by producing MCP-1 and IL-8},
  author={Kenji Hayashida and Toshihiro Nanki and Hermann Josef Girschick and S Gulderen Aktan Yavuz and Takahiro Ochi and Peter E Lipsky},
  journal={Arthritis Research},
  year={2001},
  volume={3},
  pages={118 - 126}
}
Macrophages that accumulate in the synovium of rheumatoid arthritis patients play an important role in the pathogenesis of this inflammatory disease. However, the mechanism by which macrophages are attracted into the inflamed synovium and accumulate there has not been completely delineated. The results of this study show that rheumatoid arthritis synovial stromal cells produce the chemokines monocyte chemotactic protein-1 and IL-8, and these have the capacity to attract peripheral monocytes… CONTINUE READING
57 Citations
24 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 57 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 24 references

Similar Papers

Loading similar papers…