Synovial sarcoma is a stem cell malignancy.

  title={Synovial sarcoma is a stem cell malignancy.},
  author={Norifumi Naka and Satoshi Takenaka and Nobuhito Araki and Toshitada Miwa and Nobuyuki Hashimoto and Kiyoko Yoshioka and Susumu Joyama and Ken-ichiro Hamada and Yoshitane Tsukamoto and Yasuhiko Tomita and Takafumi Ueda and Hideki Yoshikawa and Kazuyuki Itoh},
  journal={Stem cells},
  volume={28 7},
Synovial sarcoma (SS) is a malignant soft tissue tumor characterized by its unique t(X;18)(p11;q11) chromosomal translocation leading to the formation of the SS18-SSX fusion gene. The resulting fusion protein product is considered to play as an aberrant transcription factor and transform target cells by perturbing their gene expression program. However, the… CONTINUE READING