Synovial fluid biomarkers for periprosthetic infection.

  title={Synovial fluid biomarkers for periprosthetic infection.},
  author={Carl A Deirmengian and Nadim James Hallab and Abdul Rahman Tarabishy and Craig J. Della Valle and Joshua.J. Jacobs and Jess H. Lonner and Robert E. Booth},
  journal={Clinical orthopaedics and related research},
  volume={468 8},
BACKGROUND We have previously described a unique gene expression signature exhibited by synovial fluid leukocytes in response to bacterial infection, identifying a number of potential biomarkers for infection. However, the diagnostic performance of these potential biomarkers in an immunoassay format is unknown. QUESTIONS/PURPOSES We therefore evaluated the sensitivity, specificity, and accuracy of several potential synovial fluid biomarkers for infection, and compared them to current… CONTINUE READING
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