Syngenic grafting of a whole juvenile male gonadal tissue into the adult testes confers successful spermatogenesis in mice

@inproceedings{Tada2016SyngenicGO,
  title={Syngenic grafting of a whole juvenile male gonadal tissue into the adult testes confers successful spermatogenesis in mice},
  author={Norihiro Tada and Fumio Kanai and Eri Nakamura and Hongmei Lu and Masahiro Sato},
  year={2016}
}
Abstract Objective To examine whether functional spermatozoa can be obtained when a whole male gonadal tissue (testes, epididymides, and fat) isolated from neonatal mice is grafted underneath adult mouse testes. Methods Neonatal (1-day-old) male gonadal tissue, isolated from enhanced green fluorescent protein (EGFP)-transgenic (Tg) mice (C57BL/6-Tg(ACTB-EGFP)1Osb/J), was inserted deep in the testis of a non-Tg recipient mouse through a tunica albuginea incision. Two months after transplantation… CONTINUE READING

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