Synexpression groups in eukaryotes

@article{Niehrs1999SynexpressionGI,
  title={Synexpression groups in eukaryotes},
  author={Christof Niehrs and Nicolas Pollet},
  journal={Nature},
  year={1999},
  volume={402},
  pages={483-487}
}
In 1960, Jacob and Monod described the bacterial operon, a cluster of functionally interacting genes whose expression is tightly coordinated. Global expression analysis has shown that the highly coordinate expression of genes functioning in common processes is also a widespread phenomenon in eukaryotes. These sets of co-regulated genes, or ‘synexpression groups’, show a striking parallel to the operon, and may be a key determinant facilitating evolutionary change leading to animal diversity. 

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