Synergy of CpG oligodeoxynucleotide and double-stranded RNA (poly I:C) on nitric oxide induction in chicken peripheral blood monocytes.

@article{He2007SynergyOC,
  title={Synergy of CpG oligodeoxynucleotide and double-stranded RNA (poly I:C) on nitric oxide induction in chicken peripheral blood monocytes.},
  author={Haiqi He and Kenneth J. Genovese and David J. Nisbet and Michael H. Kogut},
  journal={Molecular immunology},
  year={2007},
  volume={44 12},
  pages={3234-42}
}
Toll-like receptors (TLRs) recognize microbial components and initiate the innate immune responses that control microbial infections. We have investigated the innate immune response of chicken monocytes to ligands of TLR3 and TLR9, poly I:C (an analog of viral double-stranded RNA) and CpG-ODN (a CpG-motif containing oligodeoxydinucleotide) by measuring the… CONTINUE READING