Synergy between the ectoenzymes CD39 and CD73 contributes to adenosinergic immunosuppression in human malignant gliomas.

@article{Xu2013SynergyBT,
  title={Synergy between the ectoenzymes CD39 and CD73 contributes to adenosinergic immunosuppression in human malignant gliomas.},
  author={Shuo Xu and Qian-qian Shao and Jin-Tang Sun and Ning Yang and Qi Xie and Dong-hai Wang and Qi-bing Huang and Bin Huang and Xin-Yu Wang and Xin-Gang Li and Xun Qu},
  journal={Neuro-oncology},
  year={2013},
  volume={15 9},
  pages={1160-72}
}
BACKGROUND The importance of ectoenzymes CD39 and CD73 in mediating adenosinergic immunosuppression has been recognized, but their roles in human malignant glioma-associated immunosuppression remain largely unknown. METHODS In this study, the ectoenzyme characteristics of malignant glioma cells and infiltrating CD4(+) T lymphocytes isolated from newly diagnosed malignant glioma patients were investigated. The ectoenzyme activities of both cell populations were determined by nucleotide… CONTINUE READING
Related Discussions
This paper has been referenced on Twitter 1 time. VIEW TWEETS

Citations

Publications citing this paper.
Showing 1-10 of 18 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 56 references

Immunotherapy of cancer in 2012.

CA: a cancer journal for clinicians • 2012

Involvementof ecto-5′-nucleotidase/CD73 inU138MGgliomacell adhesion

AR Cappellari, GJ Vasques, L Bavaresco, E Braganhol, AM. Battastini
Mol Cell Biochem • 2012

Similar Papers

Loading similar papers…