Synergy between sequence and size in Large-scale genomics

@article{Gregory2005SynergyBS,
  title={Synergy between sequence and size in Large-scale genomics},
  author={T. Ryan Gregory},
  journal={Nature Reviews Genetics},
  year={2005},
  volume={6},
  pages={699-708}
}
  • T. Gregory
  • Published 1 September 2005
  • Biology
  • Nature Reviews Genetics
Until recently the study of individual DNA sequences and of total DNA content (the C-value) sat at opposite ends of the spectrum in genome biology. For gene sequencers, the vast stretches of non-coding DNA found in eukaryotic genomes were largely considered to be an annoyance, whereas genome-size researchers attributed little relevance to specific nucleotide sequences. However, the dawn of comprehensive genome sequencing has allowed a new synergy between these fields, with sequence data… 
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