Synergy between acylureidopenicillins and immunoglobulin G in experimental animals.

@article{Dalhoff1984SynergyBA,
  title={Synergy between acylureidopenicillins and immunoglobulin G in experimental animals.},
  author={Axel A H Dalhoff},
  journal={The American journal of medicine},
  year={1984},
  volume={76 3A},
  pages={91-100}
}
The interaction of a commercially available 7S modified immunoserumglobulin and beta-lactam antibiotics was studied in animal experiments (granuloma pouch model) as well as an ex vivo system (rat polyvinyl sponge model). Infections of the pouches were caused by gram-negative rods and gram-positive cocci, respectively. Therapy of pouches being infected with beta-lactamase-producing strains with beta-lactam antibiotics and immunoserumglobulin was as effective as beta-lactam antibiotic monotherapy… CONTINUE READING