Synergistic targeting of cancer and associated angiogenesis using triple-targeted dual-drug silica nanoformulations for theragnostics.

@article{Veeranarayanan2012SynergisticTO,
  title={Synergistic targeting of cancer and associated angiogenesis using triple-targeted dual-drug silica nanoformulations for theragnostics.},
  author={S. Veeranarayanan and A. C. Poulose and M. S. Mohamed and S. H. Varghese and Y. Nagaoka and Yasuhiko Yoshida and T. Maekawa and D. S. Kumar},
  journal={Small},
  year={2012},
  volume={8 22},
  pages={
          3476-89
        }
}
  • S. Veeranarayanan, A. C. Poulose, +5 authors D. S. Kumar
  • Published 2012
  • Medicine
  • Small
  • The targeting and therapeutic efficacy of dye- and dual-drug-loaded silica nanoparticles, functionalized with triple targeting ligands specific towards cancer and neoangiogenesis simultaneously, are discussed. This synergized, high-precision, multitarget concept culminates in an elevated uptake of nanoparticles by cancer and angiogenic cells with amplified proficiency, thereby imparting superior therapeutic efficacy against breast cancer cells and completely disabling the migration and… CONTINUE READING
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