Synergistic interaction of topographic features in the production of bone-like nodules on Ti surfaces by rat osteoblasts.

@article{Wieland2005SynergisticIO,
  title={Synergistic interaction of topographic features in the production of bone-like nodules on Ti surfaces by rat osteoblasts.},
  author={Marco Wieland and Marcus Textor and Babak Chehroudi and D M Donald M Brunette},
  journal={Biomaterials},
  year={2005},
  volume={26 10},
  pages={1119-30}
}
The objective of this study was to study the responses of osteoblast-like cells to rough Titanium (Ti)-coated epoxy surfaces of differing topographic complexity. Four topographies were studied: polished (PO), coarse-blasted (CB), acid-etched (AE) and coarse-blasted+acid-etched (SLA). Rat osteoblasts were cultured on these surfaces and their morphology, thickness as well as the number and size of bone-like nodules measured. To determine cell shape and cell thickness, fluorescein-5… CONTINUE READING