Synergistic interaction of dietary cholesterol and dietary fat in inducing experimental steatohepatitis.

@article{Savard2013SynergisticIO,
  title={Synergistic interaction of dietary cholesterol and dietary fat in inducing experimental steatohepatitis.},
  author={Christopher E. Savard and Erica V Tartaglione and Rahul Kuver and W. Geoffrey Haigh and Geoffrey C. Farrell and Savitha Subramanian and Alan Chait and Matthew M Yeh and Lebris S Quinn and George N. Ioannou},
  journal={Hepatology},
  year={2013},
  volume={57 1},
  pages={81-92}
}
UNLABELLED The majority of patients with nonalcoholic fatty liver disease (NAFLD) have "simple steatosis," which is defined by hepatic steatosis in the absence of substantial inflammation or fibrosis and is considered to be benign. However, 10%-30% of patients with NAFLD progress to fibrosing nonalcoholic steatohepatitis (NASH), which is characterized by varying degrees of hepatic inflammation and fibrosis, in addition to hepatic steatosis, and can lead to cirrhosis. The cause(s) of progression… CONTINUE READING
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