Synergistic effects of D1/5 and 5-HT1A/7 receptor agonists on locomotor movement induction in complete spinal cord-transected mice.

@article{Lapointe2008SynergisticEO,
  title={Synergistic effects of D1/5 and 5-HT1A/7 receptor agonists on locomotor movement induction in complete spinal cord-transected mice.},
  author={Nicolas Lapointe and Pierre A. Guertin},
  journal={Journal of neurophysiology},
  year={2008},
  volume={100 1},
  pages={160-8}
}
Monoamines are well known to modulate locomotion in several vertebrate species. Coapplication of dopamine (DA) and serotonin (5-HT) has also been shown to potently induce fictive locomotor rhythms in isolated spinal cord preparations. However, a synergistic contribution of these monoamines to locomotor rhythmogenesis in vivo has never been examined. Here, we characterized the effects induced by selective DA and 5-HT receptor agonists on hindlimb movement induction in completely spinal cord… CONTINUE READING

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Coapplication of dopamine ( DA ) and serotonin ( 5-HT ) has also been shown to potently induce fictive locomotor rhythms in isolated spinal cord preparations .
Coapplication of dopamine ( DA ) and serotonin ( 5-HT ) has also been shown to potently induce fictive locomotor rhythms in isolated spinal cord preparations .
Coapplication of dopamine ( DA ) and serotonin ( 5-HT ) has also been shown to potently induce fictive locomotor rhythms in isolated spinal cord preparations .
Coapplication of dopamine ( DA ) and serotonin ( 5-HT ) has also been shown to potently induce fictive locomotor rhythms in isolated spinal cord preparations .
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