Synergistic effect of quercetin and quinic acid by alleviating structural degeneration in the liver, kidney and pancreas tissues of STZ-induced diabetic rats: a mechanistic study.

@article{Arya2014SynergisticEO,
  title={Synergistic effect of quercetin and quinic acid by alleviating structural degeneration in the liver, kidney and pancreas tissues of STZ-induced diabetic rats: a mechanistic study.},
  author={Aditya Arya and Mazen M. Jamil Al-Obaidi and Nayiar Shahid and Mohamed Ibrahim Bin Noordin and Chung Yeng Looi and Won Fen Wong and Si Lay Khaing and Mohd Rais Mustafa},
  journal={Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association},
  year={2014},
  volume={71},
  pages={
          183-96
        }
}
  • A. Arya, M. Al-Obaidi, +5 authors M. Mustafa
  • Published 1 September 2014
  • Medicine
  • Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
The aim of this study was to investigate the synergistic effects of quercetin (QE) and quinic acid (QA) on a STZ-induced diabetic rat model to determine their potential role in alleviating diabetes and its associated complications. In our study design, diabetic rats were treated with single and combined doses of QE and QA for 45days to analyse their effects on liver, kidney and pancreas tissues. The study result showed that QE and QA treated groups down-regulated hyperglycaemia and oxidative… Expand
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Diabetic Nephropathy (DN) is one of most prevalent complications of Diabetes Mellitus (DM), therefore prevention of its development is a important field for researches. Quercetin is a plant flavenoidExpand
Polyphenols-rich Vernonia amygdalina shows anti-diabetic effects in streptozotocin-induced diabetic rats.
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