Synergistic effect between apolipoprotein E and angiotensinogen gene polymorphisms in the risk for early myocardial infarction.

@article{Batalla2000SynergisticEB,
  title={Synergistic effect between apolipoprotein E and angiotensinogen gene polymorphisms in the risk for early myocardial infarction.},
  author={Alberto Batalla and Ruth Alvarez and J R Reguero and Sergio Hevia and Gustavo Iglesias-Cubero and V. Gonz{\'a}lez {\'A}lvarez and Arturo Cortina and Pelayo Gonz{\'a}lez and M M Celada and Adriana Medina and Eliecer Coto},
  journal={Clinical chemistry},
  year={2000},
  volume={46 12},
  pages={1910-5}
}
BACKGROUND Several studies based on different populations worldwide have described an association between cardiovascular diseases and genetic variations in the apolipoprotein E (A:POE), angiotensinogen (A:GT), angiotensin receptor type 1 (A:T1R), and angiotensin-converting enzyme (A:CE) genes. In addition, there is growing evidence of an interaction between hypercholesterolemia and the renin-angiotensin system in the risk for hypertension and atherosclerosis. METHODS To determine whether the… CONTINUE READING
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Apolipoprotein E4 homozygosity in young men with coronary heart disease

  • FM vanBockxmeer, Mamotte CDS
  • Lancet
  • 1992
Highly Influential
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