Synergistic cytotoxicity and DNA strand breaks in cells and plasmid DNA exposed to uranyl acetate and ultraviolet radiation.

@article{Wilson2015SynergisticCA,
  title={Synergistic cytotoxicity and DNA strand breaks in cells and plasmid DNA exposed to uranyl acetate and ultraviolet radiation.},
  author={Janice Wilson and Mary C. Zuniga and Filbert Yazzie and Diane M. Stearns},
  journal={Journal of applied toxicology : JAT},
  year={2015},
  volume={35 4},
  pages={338-49}
}
Depleted uranium (DU) has a chemical toxicity that is independent of its radioactivity. The purpose of this study was to explore the photoactivation of uranyl ion by ultraviolet (UV) radiation as a chemical mechanism of uranium genotoxicity. The ability of UVB (302 nm) and UVA (368 nm) radiation to photoactivate uranyl ion to produce single strand breaks… CONTINUE READING