Synergistic combinations of antifungals and anti-virulence agents to fight against Candida albicans.

@article{Cui2015SynergisticCO,
  title={Synergistic combinations of antifungals and anti-virulence agents to fight against Candida albicans.},
  author={Jinhui Cui and Biao Ren and Yaojun Tong and Huanqin Dai and Lixin Zhang},
  journal={Virulence},
  year={2015},
  volume={6 4},
  pages={
          362-71
        }
}
Candida albicans, one of the pathogenic Candida species, causes high mortality rate in immunocompromised and high-risk surgical patients. In the last decade, only one new class of antifungal drug echinocandin was applied. The increased therapy failures, such as the one caused by multi-drug resistance, demand innovative strategies for new effective antifungal drugs. Synergistic combinations of antifungals and anti-virulence agents highlight the pragmatic strategy to reduce the development of… CONTINUE READING
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