Synergistic antiinflammatory effect of NF-κB inhibitors and steroidal or non steroidal antiinflammatory drugs in the pleural inflammation induced by carrageenan in mice

@article{FrdeSaleh2000SynergisticAE,
  title={Synergistic antiinflammatory effect of NF-κB inhibitors and steroidal or non steroidal antiinflammatory drugs in the pleural inflammation induced by carrageenan in mice},
  author={T. S. Fr{\"o}de-Saleh and Jo{\~a}o Batista Calixto},
  journal={Inflammation Research},
  year={2000},
  volume={49},
  pages={330-337}
}
Objectives: Experiments were designed to determine whether or not inhibitors of NF-Kappa B (NF-κB) exhibit antiinflammatory effects when assessed in carrageenan-induced pleural inflammation in the mouse.¶Material and methods: Adult mice of both sexes received pyrrolidine dithiocarbamate (PDTC) or sulfasalazine administered intraperitoneal by at several time points before intrapleural injection of carrageenan (1%) and the exudation and the total and differential cells were analysed.¶Results… CONTINUE READING

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