Synergistic and drug-resistant reversing effects of diorcinol D combined with fluconazole against Candida albicans.

  title={Synergistic and drug-resistant reversing effects of diorcinol D combined with fluconazole against Candida albicans.},
  author={Y. Li and Wenqiang Chang and M. Zhang and X. Li and Y. Jiao and H. Lou},
  journal={FEMS yeast research},
  volume={15 2}
  • Y. Li, Wenqiang Chang, +3 authors H. Lou
  • Published 2015
  • Medicine, Biology
  • FEMS yeast research
  • The emergence of drug resistance and limitation of antifungal agents bring enormous challenges to the management of Candida infection. Combination therapy is a useful way to treat the fungal infection, especially for those difficult-to-treat infections. In this research, we investigated the interaction effects between diorcinol D (DD), an antifungal active natural product from lichen endophytic fungus and fluconazole (FLC) against planktonic cells and mature biofilms of Candida albicans in… CONTINUE READING
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