Synergistic and Non-synergistic Associations for Cigarette Smoking and Non-tobacco Risk Factors for Cardiovascular Disease Incidence in the Atherosclerosis Risk In Communities (ARIC) Study.

@article{Lubin2017SynergisticAN,
  title={Synergistic and Non-synergistic Associations for Cigarette Smoking and Non-tobacco Risk Factors for Cardiovascular Disease Incidence in the Atherosclerosis Risk In Communities (ARIC) Study.},
  author={Jay H. Lubin and David Couper and Pamela L Lutsey and Hiroshi Yatsuya},
  journal={Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco},
  year={2017},
  volume={19 7},
  pages={826-835}
}
Introduction Cigarette smoking, various metabolic and lipid-related factors and hypertension are well-recognized cardiovascular disease (CVD) risk factors. Since smoking affects many of these factors, use of a single imprecise smoking metric, for example, ever or never smoked, may allow residual confounding and explain inconsistencies in current assessments of interactions. Methods Using a comprehensive model in pack-years and cigarettes/day for the complex smoking-related relative risk (RR… CONTINUE READING

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