Synergistic activation of the chicken mim-1 gene by v-myb and C/EBP transcription factors.

@article{Burk1993SynergisticAO,
  title={Synergistic activation of the chicken mim-1 gene by v-myb and C/EBP transcription factors.},
  author={Oliver Burk and Sigrun Mink and M. Ringwald and Karl Heinz Klempnauer},
  journal={The EMBO journal},
  year={1993},
  volume={12 5},
  pages={2027-38}
}
The retroviral oncogene v-myb encodes a transcriptional activator which is responsible for the activation of the mim-1 gene in myelomonocytic cells transformed by v-myb. The mim-1 promoter contains several myb consensus binding sites and has previously been shown to be regulated directly by v-myb. Here we report that the mim-1 gene is activated synergistically by v-myb and different C/EBP transcription factors. We have cloned a chicken C/EBP-related gene that is highly expressed in myeloid… CONTINUE READING

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