Synergistic activation of interleukin-8 gene transcription by all-trans-retinoic acid and tumor necrosis factor-alpha involves the transcription factor NF-kappaB.

@article{Harant1996SynergisticAO,
  title={Synergistic activation of interleukin-8 gene transcription by all-trans-retinoic acid and tumor necrosis factor-alpha involves the transcription factor NF-kappaB.},
  author={Hanna Harant and Rainer de Martin and Peter Andrew and E Foglar and Ch Dittrich and Ivan J. D. Lindley},
  journal={The Journal of biological chemistry},
  year={1996},
  volume={271 43},
  pages={26954-61}
}
Induction of interleukin-8 (IL-8) by IL-1 or tumor necrosis factor (TNF), and repression by interferons or glucocorticoids have been shown to involve sequences between nucleotides -94 and -71 of the 5'-flanking region, and the transcription factors NF-IL-6 and NF-kappaB. The A3 cell line was derived from the human melanoma cell line G-361 by stable… CONTINUE READING