Synergistic Effects of Combined Cell Therapy for Chronic Ischemic Cardiomyopathy.

@article{Karantalis2015SynergisticEO,
  title={Synergistic Effects of Combined Cell Therapy for Chronic Ischemic Cardiomyopathy.},
  author={Vasileios Karantalis and Viky Y Suncion-Loescher and Luiza Lima Bagno and Samuel Golpanian and Ariel Wolf and Cristina Sanina and Courtney Heather Premer and Anthony J. Kanelidis and Frederic C McCall and Bo Wang and Wayne Erwin Balkan and Jos{\'e} Emilio Fern{\'a}ndez-Britto Rodr{\'i}guez and Marcos Rosado and Azorides R. Morales and Konstantinos E. Hatzistergos and Makoto Natsumeda and Irene S. Margitich and Ivonne Hernandez Schulman and Samirah Abreu Gomes and Muzammil Mushtaq and John F. Martin and Joel E. Fishman and P Pattany and Juan Pablo Torres Zambrano and Alan W. Heldman and Joshua M Hare},
  journal={Journal of the American College of Cardiology},
  year={2015},
  volume={66 18},
  pages={
          1990-1999
        }
}
BACKGROUND Both bone marrow-derived mesenchymal stem cells (MSCs) and c-kit(+) cardiac stem cells (CSCs) improve left ventricular remodeling in porcine models and clinical trials. Using xenogeneic (human) cells in immunosuppressed animals with acute ischemic heart disease, we previously showed that these 2 cell types act synergistically. OBJECTIVES To more accurately model clinical applications for heart failure, this study tested whether the combination of autologous MSCs and CSCs produce… CONTINUE READING
BETA

Similar Papers

Citations

Publications citing this paper.
SHOWING 1-10 OF 50 CITATIONS, ESTIMATED 57% COVERAGE

Cell Therapy Needs Rigorous Translational Studies in Large Animal Models.

  • Journal of the American College of Cardiology
  • 2015
VIEW 4 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Mesenchymal Stromal Cells as a Therapeutic Intervention

VIEW 5 EXCERPTS
CITES BACKGROUND & RESULTS
HIGHLY INFLUENCED

A Combination of Allogeneic Stem Cells Promotes Cardiac Regeneration.

  • Journal of the American College of Cardiology
  • 2017
VIEW 4 EXCERPTS
CITES RESULTS & BACKGROUND
HIGHLY INFLUENCED

Cardiovascular Regenerative Medicine

  • Springer International Publishing
  • 2019

FILTER CITATIONS BY YEAR

2015
2019

CITATION STATISTICS

  • 4 Highly Influenced Citations

  • Averaged 9 Citations per year from 2017 through 2019

References

Publications referenced by this paper.
SHOWING 1-10 OF 49 REFERENCES

The type of injury dictates the mode of repair in neonatal and adult heart

KonfinoT, LandaN, T Ben-Mordechai, J Leor
  • J Am Heart Assoc
  • 2015
VIEW 1 EXCERPT

The type of injury dictates the mode of repair in neonatal and adult heart

KonfinoT, LandaN, T Ben-Mordechai, J Leor
  • J Am Heart Assoc
  • 2015
VIEW 1 EXCERPT

cKit+ cardiac progenitors of neural crest origin.

  • Proceedings of the National Academy of Sciences of the United States of America
  • 2015
VIEW 1 EXCERPT