Synergistic Antibacterial Effect between Silibinin and Antibiotics in Oral Bacteria

@inproceedings{Lee2012SynergisticAE,
  title={Synergistic Antibacterial Effect between Silibinin and Antibiotics in Oral Bacteria},
  author={Young Soo Lee and Kyeung-Ae Jang and J D Cha},
  booktitle={Journal of biomedicine & biotechnology},
  year={2012}
}
Silibinin is a composition of the silymarin group as a hepatoprotective agent, and it exhibits various biological activities, including antibacterial activity. In this study, the antibacterial activities of silibinin were investigated in combination with two antimicrobial agents against oral bacteria. Silibinin was determined with MIC and MBC values ranging from 0.1 to 3.2 and 0.2 to 6.4  μg/mL, ampicillin from 0.125 to 64 and 0.5 to 64  μg/mL, gentamicin from 2 to 256 and 4 to 512  μg/mL… CONTINUE READING
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