Synergistic Anti-Cancer Effects of Icariin and Temozolomide in Glioblastoma

@article{Yang2014SynergisticAE,
  title={Synergistic Anti-Cancer Effects of Icariin and Temozolomide in Glioblastoma},
  author={Lijuan Yang and Yuexun Wang and Hua Guo and Meiling Guo},
  journal={Cell Biochemistry and Biophysics},
  year={2014},
  volume={71},
  pages={1379-1385}
}
Glioblastoma is an aggressive malignancy, which is associated with poor prognosis. Temozolomide (TMZ) has been showed to be an effective chemotherapeutic agent for glioblastoma treatment; however, the response rate is not satisfactory. Icariin is a natural compound with anti-cancer activity against a variety of cancers. This study is designed to determine… CONTINUE READING