Synergistic Analgesia of Duloxetine and Celecoxib in the Mouse Formalin Test: A Combination Analysis

Abstract

Duloxetine, a serotonin and noradrenaline reuptake inhibitor, and celecoxib, a non-steroidal anti-inflammatory drug, are commonly used analgesics for persistent pain, however with moderate gastrointestinal side effects or analgesia tolerance. One promising analgesic strategy is to give a combined prescription, allowing the maximal or equal efficacy with… (More)
DOI: 10.1371/journal.pone.0076603

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Cite this paper

@inproceedings{Sun2013SynergisticAO, title={Synergistic Analgesia of Duloxetine and Celecoxib in the Mouse Formalin Test: A Combination Analysis}, author={Yong-hai Sun and Yu-Lin Dong and Yu-tong Wang and Guo-Li Zhao and Gui-Jun Lu and Jing Yang and Shengxi Wu and Ze-xu Gu and Ruiping Wang}, booktitle={PloS one}, year={2013} }