Synergistic Analgesia of Duloxetine and Celecoxib in the Mouse Formalin Test: A Combination Analysis

@inproceedings{Sun2013SynergisticAO,
  title={Synergistic Analgesia of Duloxetine and Celecoxib in the Mouse Formalin Test: A Combination Analysis},
  author={Yong-hai Sun and Yu-Lin Dong and Yu-tong Wang and Guo-Li Zhao and Gui-Jun Lu and Jing Yang and Sheng-xi Wu and Ze-xu Gu and Wen Wang},
  booktitle={PloS one},
  year={2013}
}
Duloxetine, a serotonin and noradrenaline reuptake inhibitor, and celecoxib, a non-steroidal anti-inflammatory drug, are commonly used analgesics for persistent pain, however with moderate gastrointestinal side effects or analgesia tolerance. One promising analgesic strategy is to give a combined prescription, allowing the maximal or equal efficacy with… CONTINUE READING