Synergisms with mixtures of xenoestrogens: a reevaluation using the method of isoboles.

@article{Kortenkamp1998SynergismsWM,
  title={Synergisms with mixtures of xenoestrogens: a reevaluation using the method of isoboles.},
  author={Andreas Kortenkamp and Rolf Altenburger},
  journal={The Science of the total environment},
  year={1998},
  volume={221 1},
  pages={59-73}
}
There are concerns about possible combination effects of environmental chemicals with oestrogenic activity and their implications for human health. Such chemicals are present in complex mixtures in our environment. A number of studies searching for possible synergistic interactions between xenoestrogens have appeared in the literature. However, in these studies no account was taken of established concepts and methods for analysing combination effects. In the present review, we highlight… CONTINUE READING

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