Synergism between BCNU and irradiation in the treatment of anaplastic gliomas. An in vivo study using the avian sarcoma virus-induced glioma model.

Abstract

The therapeutic effects of irradiation, BCNU, or combined irradiation and BCNU were studied in the avian sarrcoma virus (ASV)-induced glioma model in rats. Whole-head orthovoltage radiation therapy was given in six equal fractions over 2 weeks, and BCNU was administered intraperitoneally as a single dose of 10 mg/kg. Two series of experiments were performed… (More)

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@article{Steinbok1979SynergismBB, title={Synergism between BCNU and irradiation in the treatment of anaplastic gliomas. An in vivo study using the avian sarcoma virus-induced glioma model.}, author={Paul Steinbok and M. Stephen Mahaley and Raghavendra Udupa U and Daniel Zinn and Stanley Lipper and J L Mahaley and Darell D Bigner}, journal={Journal of neurosurgery}, year={1979}, volume={51 5}, pages={581-6} }