• DOI:10.1212/WNL.5.6.373
• Corpus ID: 44664860

Syndrome of Klüver and Bucy

@article{Terzian1955SyndromeOK,
  title={Syndrome of Klüver and Bucy},
  author={H. D. Terzian and Giuaeppe Dalle Ore},
  journal={Neurology},
  year={1955},
  volume={5},
  pages={373 - 373}
}

• H. Terzian, Giuaeppe Dalle Ore
• Published 1 June 1955
• Psychology, Biology
• Neurology

IN 1937 Kliiver and Bucy’ described some behavior changes which represent “the most striking behavior changes ever produced in animals” as a result of bilateral operative removal of the temporal lobes, including most of the uncus and hippocampus in the Macacus rhesus. These behavior changes consisted of 1) “psychic blindness” or “visual agnosia;” 2) strong oral tendencies; 3) the socalled “hypermetamorphosis” or excessive tendency to attend and react to every visual stimulus; 4 ) considerable changes in emotional behavior characterized by a remarkable decrease of aggressive behavior and by loss of fear reactions; 5 ) an increased sexual activity involving forms of heterosexual, homosexual, and autosexual behavior; and 6) considerable changes in dietary habits.= In Kliiver and Bucy’s experimental work this syndrome was not produced by lesions of other lobes, or by unilateral temporal lesions, or by removal only of the lateral temporal cortex both unilateral or bilateral. The experimental work of Kliiver and Bucy was supported more recently by Thomson and Walkere who studied the effects of minor rhinencephalic removals in the Macacus rhesus, by Bard7 in the same animal, and by Gastauts and Schreiner and KlingS in cats. Bard and Mountcastlelo had, on the other hand, demonstrated that bilateral removal of practically the same rhinencephalic structures in cats produces savageness and a considerable increase of rage reactions. Bard and Mountcastle, who succeeded in converting a placid state produced in cats by neocortical removal to one of ferocity by removal of “pyriform lobe, amygdala, and hippocampus,” put forth the hypothesis that the amygdala “acts as a funnel through which inhibitory influences originating