Syndrome de Gilles de la Tourette : défis de la recherche pour améliorer la pratique clinique

  title={Syndrome de Gilles de la Tourette : d{\'e}fis de la recherche pour am{\'e}liorer la pratique clinique},
  author={Simon Morand-Beaulieu and Julie B. Leclerc},
  journal={Encephale-revue De Psychiatrie Clinique Biologique Et Therapeutique},


Treatment strategies for tics in Tourette syndrome
There are a number of agents that are clearly useful as first-line treatments for TS and other interventions may be of most benefit to patients exhibiting refractory tics or more specific symptom profiles.
Gilles de la Tourette syndrome as a paradigmatic neuropsychiatric disorder
The clinical phenomenology of motor and vocal tics and associated sensory experiences (premonitory urges) as well as the behavioral spectrum of the most common comorbidities, including obsessive-compulsive disorder, attention-deficit and hyperactivity disorder, affective symptoms, and impulsivity are encompassed.
Tourette syndrome in a longitudinal perspective. Clinical course of tics and comorbidities, coexisting psychopathologies, phenotypes and predictors.
  • C. Groth
  • Psychology, Medicine
    Danish medical journal
  • 2018
The clinical course of TS during adolescence was confirmed, with solid evidence, with decline in tics, OCD and ADHD severity, and several predictors were found to predict the clinical Course of TS in adolescence and early adulthood.
Clinical course of Tourette syndrome.
A Therapy for Tics in Children Managing Underlying Processes: a Pilot Study
The cognitive psychophysiological treatment reduced severity of tics in children and adolescents as well as in adults, highlighting the necessity for a therapeutic approach which focuses on the central and global processes surrounding tics to help symptom reduction in people with Tourette.
Randomized trial of behavior therapy for adults with Tourette syndrome.
Comprehensive behavior therapy is a safe and effective intervention for adults with Tourette syndrome and patients receiving behavior therapy who were available for assessment at 6 months after treatment showed continued benefit.
The Role of Atypical Antipsychotics for Treatment of Tourette’s Syndrome: An Overview
An updated overview of the role of atypical antipsychotics for treatment of Tourette’s syndrome is provided, with evidence-based guidance on their use.
Caudate volumes in childhood predict symptom severity in adults with Tourette syndrome
Caudate volumes in children with Tourette syndrome predict the severity of tic and obsessive–compulsive symptoms in early adulthood, providing compelling evidence that morphologic disturbances of the caudate nucleus within cortico-striatal-thalamo-cortical circuits are central to the persistence of both tics and OCD symptoms into adulthood.
Tourette's syndrome