Syndecans in inflammation.

@article{Gtte2003SyndecansII,
  title={Syndecans in inflammation.},
  author={Martin G{\"o}tte},
  journal={FASEB journal : official publication of the Federation of American Societies for Experimental Biology},
  year={2003},
  volume={17 6},
  pages={575-91}
}
  • Martin Götte
  • Published 2003 in
    FASEB journal : official publication of the…
Cell surface heparan sulfate (HS) influences a multitude of molecules, cell types, and processes relevant to inflammation. HS binds to cell surface and matrix proteins, cytokines, and chemokines. These interactions modulate inflammatory cell maturation and activation, leukocyte rolling, and tight adhesion to endothelium, as well as extravasation and chemotaxis. The syndecan family of transmembrane proteoglycans is the major source of cell surface HS on all cell types. Recent in vitro and in… CONTINUE READING

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Glycosaminoglycans and their proteoglycans: host-associated molecular patterns for initiation and modulation of inflammation.

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