Syndecans and the lymphoid system.

  title={Syndecans and the lymphoid system.},
  author={L{\'a}szl{\'o} Kopper and Anna Sebesty{\'e}n},
  journal={Leukemia & lymphoma},
  volume={38 3-4},
Syndecans, transmembrane proteoglycans, play an important role in cell-matrix and cell-cell interactions, as well as modulators in receptor activation. These functions are partly non-specific and related to the heparan sulfate chains attached to the ectodomain, and partly specific due to the transmembrane and cytoplasmic domains of the core protein. In hemopoietic cells syndecan-1 is expressed only in B cells at certain differentiation stages (pre-B and plasma cells). In lymphoproliferative… CONTINUE READING

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