Syndecan-1 in Cancer: Implications for Cell Signaling, Differentiation, and Prognostication


Syndecan-1, a cell surface heparan sulfate proteoglycan, is critically involved in the differentiation and prognosis of various tumors. In this review, we highlight the synthesis, cellular interactions, and the signalling pathways regulated by syndecan-1. The basal syndecan-1 level is also crucial for understanding the sequential changes involving malignant… (More)
DOI: 10.1155/2015/796052


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