Synchronous replication initiation of the two Vibrio cholerae chromosomes

@article{Egan2004SynchronousRI,
  title={Synchronous replication initiation of the two Vibrio cholerae chromosomes},
  author={Elizabeth S. Egan and Anders L\obner-Olesen and Matthew K Waldor},
  journal={Current Biology},
  year={2004},
  volume={14},
  pages={R501-R502}
}
The genome of Vibrio cholerae, the causative agent of cholera, is divided between two circular replicons. Genomic analysis has revealed that several other bacterial species have more than one chromosome. However, to date, the dynamics of chromosome replication in bacteria with more than one chromosome have not been investigated. As in V. cholerae chromosome II (1.07 Mb) is smaller than chromosome I (2.96 Mb) and contains fewer essential genes, it was proposed that it originated as a plasmid [1… CONTINUE READING
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