Synchronous pancreatic adenocarcinoma and intrahepatic cholangiocarcinoma arising in the context of intraductal papillary neoplasms.

@article{Bansal2016SynchronousPA,
  title={Synchronous pancreatic adenocarcinoma and intrahepatic cholangiocarcinoma arising in the context of intraductal papillary neoplasms.},
  author={Anmol Gupta Bansal and Swan N. Thung and Hongfa Zhu and Myron Eliot Schwartz and Sara Lewis},
  journal={Clinical imaging},
  year={2016},
  volume={40 5},
  pages={897-901}
}
Field cancerization theory provides rationale for the development of multiple pancreatic ductal and biliary lesions in a single patient through the development and accumulation of multiple genetic changes. Genetic alterations result in the development of precursor lesions including intraductal papillary mucinous neoplasms of the pancreas (IPMN), intraductal papillary neoplasm of the bile duct (IPN-B), and their malignant counterparts, pancreatic adenocarcinoma and cholangiocarcinoma. Although… CONTINUE READING
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