Synchronous differentiation of Trypanosoma brucei from bloodstream to procyclic forms in vitro.

@article{Ziegelbauer1990SynchronousDO,
  title={Synchronous differentiation of Trypanosoma brucei from bloodstream to procyclic forms in vitro.},
  author={Karl B Ziegelbauer and Michael Quinten and Heinz J. Schwarz and Terry W. Pearson and Peter Overath},
  journal={European journal of biochemistry},
  year={1990},
  volume={192 2},
  pages={373-8}
}
The differentiation of mammalian stage Trypanosoma brucei bloodstream forms comprising predominantly parasites of intermediate and stumpy morphology to the procyclic forms characteristic for the insect midgut stage was studied in vitro. Differentiation of the cell population occurred synchronously as judged by the synthesis of the surface glycoprotein, procyclin, characteristic of the arising procyclic forms and the loss of the membrane-form variant surface glycoprotein, the coat protein of… CONTINUE READING