Synchronization of chaotic early afterdepolarizations in the genesis of cardiac arrhythmias.


The synchronization of coupled oscillators plays an important role in many biological systems, including the heart. In heart diseases, cardiac myocytes can exhibit abnormal electrical oscillations, such as early afterdepolarizations (EADs), which are associated with lethal arrhythmias. A key unanswered question is how cellular EADs partially synchronize in… (More)
DOI: 10.1073/pnas.0809148106

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