Synaptotagmins in neurodegeneration.

  title={Synaptotagmins in neurodegeneration.},
  author={Gordana Glavan and Reinhard Schliebs and Marko Živin},
  journal={Anatomical record},
  volume={292 12},
Synaptotagmins (Syts) are transmembrane proteins involved in the regulation of membrane trafficking. Here, we summarize literature data that provide growing evidence that several Syts are involved in the pathophysiological mechanisms of temporal lobe epilepsy and Parkinson's disease, as well as few reports related to brain ischemia and Alzheimer's disease (AD). We also report new data from our laboratories, showing changes of the expression of several Syts in Tg2576 mouse model of AD that may… CONTINUE READING
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