Synaptophysin immunoreactivity in the cochlear nucleus after unilateral cochlear or ossicular removal.

@article{Benson1997SynaptophysinII,
  title={Synaptophysin immunoreactivity in the cochlear nucleus after unilateral cochlear or ossicular removal.},
  author={Christina G Benson and J{\'u}lia Silveira Gross and Sanoj K. Suneja and Steven J Potashner},
  journal={Synapse},
  year={1997},
  volume={25 3},
  pages={243-57}
}
This study determined if unilateral cochlear removal in adult guinea pigs led to synaptic loss followed by synaptogenesis in the cochlear nucleus (CN) and if unilateral middle ear ossicle removal led to synaptic loss in the CN. Synaptic endings were identified immunohistochemically, using a monoclonal antibody to synaptophysin. Immunolabeling was quantified densitometrically in the CN 4-161 days after cochlear removal and 161 days after ossicle removal. Fiber degeneration was visualized with… CONTINUE READING

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