Synaptophysin immunohistochemistry in the human cochlea.

  title={Synaptophysin immunohistochemistry in the human cochlea.},
  author={Shaden Ali M Khalifa and Ulla Friberg and Robert Illing and Helge Rask-Andersen},
  journal={Hearing research},
  volume={185 1-2},
Light microscopy and immunohistochemical analyses of a freshly prepared human cochlea, removed at meningioma skull base surgery, were performed with particular emphasis on synaptophysin (SY) reactivity. Synaptophysin, a 38-kDa glycoprotein, is one of the most abundant integral membrane proteins of small presynaptic vesicles and is a useful marker for sites of synaptic transmission of the efferent olivocochlear system in the cochlea. Following fixation and decalcification, cryosections of 30… CONTINUE READING