Synaptonemal complex proteins: occurrence, epitope mapping and chromosome disjunction.

  title={Synaptonemal complex proteins: occurrence, epitope mapping and chromosome disjunction.},
  author={Melanie J. Dobson and Ronald E. Pearlman and Angelo Karaiskakis and Barbara Spyropoulos and Peter B. Moens},
  journal={Journal of cell science},
  volume={107 ( Pt 10)},
We have used polyclonal antibodies against fusion proteins produced from cDNA fragments of a meiotic chromosome core protein, Cor1, and a protein present only in the synapsed portions of the cores, Syn1, to detect the occurrence and the locations of these proteins in rodent meiotic prophase chromosomes. The 234 amino acid Cor1 protein is present in early unpaired cores, in the lateral domains of the synaptonemal complex and in the chromosome cores when they separate at diplotene. A novel… CONTINUE READING
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