Synaptojanin 2, a novel synaptojanin isoform with a distinct targeting domain and expression pattern.

@article{Nemoto1997Synaptojanin2A,
  title={Synaptojanin 2, a novel synaptojanin isoform with a distinct targeting domain and expression pattern.},
  author={Yasuo Nemoto and M. T. Verde Arribas and Christof Haffner and Pietro DeCamilli},
  journal={The Journal of biological chemistry},
  year={1997},
  volume={272 49},
  pages={30817-21}
}
Synaptojanin (synaptojanin 1) is a recently identified inositol 5'-phosphatase, which is highly enriched in nerve terminals and is implicated in synaptic vesicle recycling. It is composed of three domains: an amino-terminal SacI homology region, a central inositol 5'-phosphatase homology region, and a carboxyl-terminal proline-rich region. We have now identified and characterized a novel form of synaptojanin, synaptojanin 2, which has a broader tissue distribution. Synaptojanin 2 cDNA from rat… CONTINUE READING

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