Synaptically induced sodium signals in hippocampal astrocytes in situ.

  title={Synaptically induced sodium signals in hippocampal astrocytes in situ.},
  author={Julia Langer and Christine R Rose},
  journal={The Journal of physiology},
  volume={587 Pt 24},
Astrocytes are in close contact to excitatory synapses and express transporters which mediate the sodium-dependent uptake of glutamate. In cultured astrocytes, selective activation of glutamate transport results in sodium elevations which stimulate Na(+)/K(+)-ATPase and glucose uptake, indicating that synaptic release of glutamate might couple excitatory neuronal activity to glial sodium homeostasis and metabolism. Here, we analysed intracellular sodium transients evoked by synaptic stimulation… CONTINUE READING
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